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Thyroid stimulating hormone (TSH or thyrotropin) is secreted by the anterior lobe of the pituitary gland, and induces the production and release of thyroxine (T4) and triiodothyronine (T3) from thethyroid gland. TSH is recognized as an important measurement in the assessment of thyroid function. Although the concentration of TSH in the blood is extremely low, it is essential in the maintenanceof normal thyroid function.
ichroma™ TSH Test is based on fluorescence immunoassay technology. ichroma™ TSH uses a sandwich immunodetection method, such that by mixing detector buffer with blood specimen in test vial, the fluorescence-labeled detector anti- TSH antibody in buffer binds to TSH antigen in blood specimen. The sample mixture is loaded and migrates on the matrix of test cartridge; the complexes of detector antibody and TSH are captured to anti-TSH sandwich pair antibody that has been immobilized on test matrix.