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Follicle-stimulating hormone (FSH) is synthesized and secreted by gonadotroph cells of the anterior pituitary gland. FSH regulates thedevelopment, growth, pubertal maturation, and reproductive processes of the body. FSH and Luteinizing hormone (LH) actsynergistically in reproduction. Conditions with high FSH levelsinclude: Premature menopause also known as Premature Ovarian Failure, Poor ovarian reserve also known as Premature Ovarian Aging, Gonadal dysgenesis, Turner syndrome, Castration, Swyer syndrome, Certain forms of Congenital adrenal hyperplasia(CAH),Testicular failure. High FSH levels are an indication of subfertilityand/or infertility.
ichroma™ FSH Test is based on fluorescence immunoassay technology. ichroma™ FSH uses a sandwich immunodetection method, such that by mixing detector buffer with blood specimen in test vial, the fluorescence-labeled detector anti-FSH antibody in buffer binds to FSH antigen in blood specimen. The sample mixture is loaded and migrates on the matrix of test cartridge; the complexes of detector antibody and FSH are captured to anti-FSH sandwich pair antibody that has been immobilized on test matrix.