i-CHROMA Ferritin

i-CHROMA Ferritin

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Ferritin, a major iron storage protein, is essential to iron homeostasis and is involved in a wide range of physiologic and pathologic processes. In clinical medicine, ferritin is predominantly utilized as a marker of total body iron stores. In cases of iron deficiency and overload, serum ferritin serves a critical role in bothdiagnosis and management. Patients with ferritin levels that arehigher than the reference range may be indicative of conditions such as iron overload, infections, inflammations, collagen diseases, hepatic diseases, neoplastic disease and chronic renal failure.

Test Principle
ichroma™ Ferritin Test is based on fluorescence immunoassay technology. ichroma™ Ferritin uses a sandwich immunodetection method, such that by mixing detector buffer with blood specimen in test vial, the fluorescence-labeled detector anti-Ferritin antibody in buffer binds to Ferritin antigen in blood specimen. The sample mixture is loaded and migrates on the matrix of test cartridge; the complexes of detector antibody and Ferritin are captured to anti-Ferritin sandwich pair antibody that has been immobilized on test matrix.
Test Duration
Test takes approx. 10 minutes
Analytical Range
10~1,000 ng/mL
• Sample Type : Plasma/Serum
• Precision: CV < 10%
• Linearity: 7.8~1,000 ng/mL (R=0.986)