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CK-MB: Cardiac troponins are currently the most sensitive and specificbiochemical markers of myocardial necrosis. The clinical measurement of serum cardiac troponin-I (Tn-I) has become an important tool in the diagnosis of acute myocardial infarction.Blood concentration of Troponin-I in healthy adults is below 1.5 ng/ml but it shows great increase in several malignant diseasesmostly primary coronary syndrome, myocardial injury andinfarction.
ichroma™ Tn-I Test is based on fluorescence immunoassay technology. ichroma™ Tn-I uses a sandwich immunodetection method, such that by mixing detector buffer with blood specimen in test vial, the fluorescence-labeled detector anti-Tn-I antibody in buffer binds to Tn-I antigen in blood specimen. The sample mixture is loaded and migrates on the matrix of test cartridge; the complexes of detector antibody and Tn-I are captured to anti-Tn-I sandwich pair antibody that has been immobilized on test matrix.