SALSA MLPA kits for copy number quantification
MLPA ® is the gold standard for DNA copy number quantification and is used to study both hereditary disorders and tumours. MLPA can also be used to determine if a known mutation is present in the DNA or to investigate the methylation status of DNA sequences. MRC-Holland, the inventor and exclusive manufacturer of MLPA assays, offers more than 400 different MLPA panels used for DNA copy number quantification, mutation identification, and DNA methylation status.
Popular MLPA applications
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Predisposition to Cancer
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Neuromuscular Disorders
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Intellectual Disability
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Microdeletion, PWS/AS, FMR1/AFF2, MECP2, Sotos, WBS, SHOX, aneuploidy
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Solid Tumours
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Methylation profiling
Advantages and features of MLPA
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Examine up to 60 targets per reaction
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Only 50ng of DNA is required per reaction
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MLPA detects a short sequence of 60-80 nucleotides
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Detection of single exon deletions and duplications
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Detection of targeted point mutations
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One simple protocol for >400 applications
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Results available within 24 hours
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Limited lab equipment required: only a thermocycler and a sequence type electrophoresis system
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User-friendly, reliable, and free data analysis software, Coffalser.Net TM
Visit the MLPA website www.mlpa.com to:
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Search for genes, and chromosomal regions of interest to find all related MLPA products
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Explore the MLPA procedure to learn how to do MLPA
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Get MLPA support by viewing education, workshop, and troubleshooting material
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Stay up to date with current MLPA news